Studies on the Pathogenesis of Type I Diabetes Mellitus
نویسندگان
چکیده
منابع مشابه
On type 1 diabetes mellitus pathogenesis
Type 1 diabetes mellitus (T1DM) results from the autoimmune destruction of β cells of the endocrine pancreas. Pathogenesis of T1DM is different from that of type 2 diabetes mellitus, where both insulin resistance and reduced secretion of insulin by the β cells play a synergistic role. We will present genetic, environmental and immunologic factors that destroy β cells of the endocrine pancreas a...
متن کاملPathogenesis of type 2 diabetes mellitus.
This article provides an overview of the pathogenesis of type 2 diabetes mellitus. Discussion begins by describing normal glucose homeostasis and ingestion of a typical meal and then discusses glucose homeostasis in diabetes. Topics covered include insulin secretion in type 2 diabetes mellitus and insulin resistance, the site of insulin resistance, the interaction between insulin sensitivity an...
متن کاملThe Prevalence of Limited Joint Mobility in Patients with Type I Diabetes Mellitus in Kerman
Background & Aims: Limited joint mobility (LJM) is a complication of diabetes mellitus, which usually begins from the small joints of hands and is associated with long-term complications of diabetes, such as retinopathy and nephropathy. The aim of this study was to find the prevalence of Limited Joint Mobility in patients with type 1 diabetes mellitus in Kerman in 2003. Methods: Sixty-six patie...
متن کاملThe Pathogenesis of Diabetes Mellitus *
It was originally maintained by Naunyn that, with very rare exceptions, the underlying cause of diabetes was an inborn biologic inferiori-ty, primarily of the pancreatic reserve. Recently, Joslin27 has written, "Ever increasing evidence points strongly to the validity of the Naunyn conception of the unilty of diabetes with heredity as the common bond." Wilder41 opens his discussion of the patho...
متن کامل[Pathogenesis of diabetes mellitus].
Following the discovery of von Mering and Minkowski (1889) that diabetes followed pancreatectomy, and the later discovery that a pancreatic hormone, insulin, would reverse all the changes characteristic of diabetes, it became natural to regard diabetes mainly as an insulin-deficiency syndrome. Certainly many cases of human diabetes are due to deficiency of insulin, as evidenced by the low blood...
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ژورنال
عنوان ژورنال: Folia Endocrinologica Japonica
سال: 1990
ISSN: 0029-0661
DOI: 10.1507/endocrine1927.66.3_145